What is is supposed to do? It induces ovulation by fooling your body into believing that there is less estrogen. In the beginning, Clomid is taken at a dose of 50 mg per day for five days in the beginning at the cycle. I had a couple days of spotting that is since gone. Since you have gotten the effect of Clomid to ovulation, you may wonder whether Clomid is right choice for you or not. Zero chances getting pregnant, even with Clomid.
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It induces ovulation by fooling your body into believing that there is less estrogen. This leads to an increased production of a hormone called GnRH, causing the pituitary to pump out more of another hormone called FSH and LH, thus inducing ovulation. Ovulation is the release of the egg from the ovary. The release of the egg is necessary for your regular menstrual cycle and pregnancy to begin.
Ovulation is preceded by a long chain of events involving several hormones beginning in your prior menstrual cycle. Towards the end of a normal regular cycle, two hormones, estrogen and progesterone, slowly decrease. This eventually triggers in the first days of the next menstrual cycle a hormone called GnRH which is produced in a portion of the brain called the hypothalamus.
FSH is responsible for the growth of the follicles and eggs, and it increases the size and number of the follicles and helps to trigger ovulation. It is responsible for many functions in your body including the development of the egg in the ovary and the uterine lining. In some medical conditions such as polycystic ovary syndrome there is too much estrogen. If your body believes there is less estrogen, it will produce more GnRH, causing the pituitary to pump out more of FSH and LH eventually triggering the release of an egg from the ovary.
Clomid is usually given as a pill once a day for 5 days. The first pill of Clomid is usually started 2 to 5 days after the first day of you menstrual bleeding cycle day and ovulation usually happens days after the last dose of Clomid. Your chances of getting pregnant with Clomid are very good as long as you take it for the right reasons and have some tests done before to excluide certain problems. About three fourths of women with PCOS that are not ovulating will ovulate on Clomid at some dosing level.
But it also depends on a woman's age and other factors. In-vitro fertilization may improve pregnancy chances. Most twins conceived with Clomid will be so called "dizygotic" twins, twins that are not identical. That is because clomid leads to multiple ovulations, and non-identical twins are twins resulting from separate eggs and fertilizations with different sperm, while identical or monozygotic twins results from the splitting of a single fertilized identical egg and sperm.
No matter how well clomiphene works to make you ovulate, you will have difficulties getting pregnant unless you have good enough quality eggs, his sperms are OK, your tubes are open and you are at the optimal weight. Some women take Clomid and use ovulation predictor kits to time intercourse with ovulation. Many doctors however will monitor you using ultrasound equipment and blood work to tell you the best time to try to conceive or may combine it with a treatment like IUI.
Ovulation prediction kits are sensitive to the luteinizing hormone LH. While most medications will have no effect on the test results, there are a certain sector of medications that can have a very real effect. These medications are often prescribed for infertility. If a woman is not producing enough LH she may not be able to conceive. For this reason, some infertility medications contain LH to improve the chances of fertility.
Several infertility medications can cause the ovulation kit to test falsely positive. These include Clomid, Pergonal, Humegon and Repronex. Clomid can cause an ovulation prediction kit to test positive even when the woman is not ovulating. According to the manufacturer of Clomid, three days should pass between the last day taking the Clomid and the first day testing for ovulation. For instance, if the medication is taken for 10 days, it is okay to start using the ovulation prediction kit on the 14th day.
There could be enough LH in these medications to boost the natural LH levels to a point that looks like a spike. While this spike will not be the true spike noticed immediately before ovulation, the test will not be able to differentiate the difference between the two. Other infertility medications like Gonal-F, Follistem and Fertinex contain only the follicle stimulating hormone. These should not have any effect on the ovulation prediction kit as the kit does not test for FSH. Before starting to use an ovulation prediction kit, make sure to ask a pharmacist or your prescribing physician whether the medication causes a boost in natural LH or contains LH.
Like all fertility treatments, there are no guarantees. Even if you do ovulate while on clomid, you still need the egg and sperm to meet, for fertilization to occur and then implantation. Some women will become pregnant and others will move onto other treatments. Before taking Clomid you should have some tests done to make sure you take it for the right reasons.
Do a sperm count before starting to take Clomid. It makes no sense taking Clomid when he has a low sperm count! Pelvic sonogram to check for fibroids and ovarian cysts If a woman is menstruating, even if irregularly, clomiphene is usually effective. Women with irregular menstrual cycles ovulate infrequently. They are usually excellent candidates for clomiphene treatment since more frequent ovulation presents more opportunities to become pregnant.
The mode of action and mechanism of Clomid is fairly similar to the endogenous hormone, estrogen. Just like the estrogen, Clomid comes in contact with a receptor that is present on the hypothalamus an endocrine gland located in the brain. As the clomid blocks the way of estrogen to attach itself to the receptor, the body believes that there is not enough estrogen present. If Clomid works this way then the body ends up ovulating more frequently.
There are several other factors that can affect the chances of getting pregnant such as age and weight of women. The doctors may increase the dose as time goes by in order to increase the chances of conceiving the baby as low dose may not suffice in all patients. Even we know the postive effect clomid for ovulation, like all pharmacological preparation, use of Clomid is also associated with certain adverse events:.
Clomid was initially used for the management of infertility due to polycystic ovaries or for the treatment of PCOD polycystic ovarian disease. It has also been used successfully for the management of unexplained infertility where no other cause is identifiable. It can be used alone or in association with other drugs such as Metformin to treat fertility issues. Since you have gotten the effect of Clomid to ovulation, you may wonder whether Clomid is right choice for you or not.
According to recent data, Clomid can stimulate ovaries to release egg but does not otherwise offer any help. Currently, Clomid is only recommended if a female is using other fertility options such as IU intrauterine insemination or similar choices. Clomid is usually consumed in a dose of one to four tablets depending upon the advice of your healthcare provider. It is important to take all the pills at the same time every day.
The pharmacological preparation is available in the form of tablets starting from fifth to ninth day of period cycle. In most cases, the treatment should be continued for up to six months. If a woman has regular cycles then she should ideally start the medicine from the second day of her cycle. If the cycles are irregular, you may require a check-up from the doctor prior to initiating the therapy.
In all such cases, there is other hormonal preparation available such as progesterone and estrogen that may be used simultaneously to keep cycles regular and enhance the chances of conception. Most women conceive in the first six months; however, some may require a longer period with this therapy alone. The doctors may monitor the cycles and alter the doses, so it is highly recommended to keep up with periodic physical examinations.