Clomid is often a desirable first step for fertility treatment due to its relatively low cost. Clomid success rates are typically high. In this article, we list a number of common factors that affect fertility. We also explain ways that Clomid may help or may not help you overcome these specific fertility issues. For more information about how Clomid may help you personally, see a fertility specialist in your area.
Due to this ovulation boost, most women have a 50 percent chance of getting pregnant within the first six months after starting Clomid. Before you try to get pregnant with Clomid, make efforts to get to a healthy weight. Ask your doctor about a safe weight-loss plan that includes a healthy diet and regular exercise. Dosage Clomid success rates are affected by dosage. Most women start with a 50 mg dose of Clomid. If this initial dose does not help you ovulate, your doctor may increase your dosage by 50 mg increments in subsequent cycles.
If taking Clomid fails to help you ovulate after four to six cycles, your doctor will probably take you off this fertility drug and move on to another option. Understanding how to optimize each treatment cycle can help couples achieve success with Clomid treatment. Clomid is an anti-estrogen medication that works by blocking the estrogen receptors in the hypothalamus. As a result, follicle-stimulating hormone FSH production by the pituitary gland increases, resulting in the development of one or more follicles inside the ovaries.
About a week after the last dose of Clomid, ovulation will occur when a surge of luteinizing hormone from the pituitary gland stimulates the developing egg inside the follicle s to mature and release. How much does Clomid cost? Clomid is an affordable medication commonly covered by insurance providers that only costs a few dollars. Where can a Clomid prescription be filled? Clomid prescribed by your physician can easily be obtained by most local pharmacies, whether they specialize in fertility medications or not.
What are the common side effects? Though it is generally well tolerated, Clomid can lead to cervical mucus changes and thinning of the uterine lining that can negatively impact success rates. For this reason, a full fertility evaluation looking at the sperm quality through a semen analysis and confirming that the tubes are open with an HSG , should be completed prior to starting any treatment, including Clomid.
Why spend time on a treatment that may not work due to other unforeseen factors? Monitoring appointments consist of an ultrasound and bloodwork. The ultrasound, completed intravaginally, allows the physician to visualize the thickness of the uterine lining and the ovaries, more specifically the number of follicles within them. The bloodwork shows the trend of pre to post-stimulation hormone levels; increased levels of estrogen indicate follicular development.
These two measures of the progress of the cycles tells physicians about three important events during stimulation. This seems like a no-brainer, but the first thing a physician learns from monitoring the progress of the cycle is if a follicle was recruited and developed. Finding the correct dosage that results in the development of a single follicle in the beginning is a bit of guess and check.
Some women will respond to a 25 mg dose, while others can require up to mg before follicular development starts to occur. Starting with a conservative dose until the physician knows how a patient will respond is the best approach, as overstimulation can result in the development of more than one follicle and, as a result, an increased risk of multiples. In an unmonitored cycle, the physician would base the response to medication solely on if the cycle resulted in a pregnancy and then adjust the dosage accordingly.
Lack of response indicates to the physician a higher dosage of medication is needed. This higher dose can start the same day since the patient is still in the follicular phase of her cycle. The ability to know that the dosage was ineffective early in the treatment cycle saves the patient nearly an entire month. Is the lining thick enough for implantation? The second factor that monitoring can tell a physician is how the lining responded to the Clomid. Some patients using Clomid will suffer from a thinning of the uterine lining, making for a less than optimal environment for embryo implantation.
Should this occur, physicians can help to supplement the thickening of the lining with an estrogen suppository. Was there an over-response to medication? Unmonitored cycles can result in an increased chance of multiples, which is risky for both mother and babies. Multiples can occur when several follicles are developed and ovulated in a single cycle.
Monitoring can tell the physician when an unsafe number of follicles have been developed, allowing them to advise the patient to abstain from intercourse to avoid the increased risk of a higher order pregnancy. While under the care of a reproductive endocrinologist, the stimulation phase of a Clomid cycle in most cases ends with a trigger shot.