Lorazepam is a benzodiazepine drug with a short to medium duration of action. Its principle use is the treatment of severe chronic anxiety. The benzodiazepines are a group of over 20 structurally related central nervous depressant drugs. They are widely prescribed for the treatment of anxiety, stress and insomnia. They are also used as pre-medication, for the induction of general anaesthesia and for treatment of alcohol withdrawal, epileptic seizures and muscle spasms. Benzodiazepines are potentially addictive and are taken for their mood-altering properties. They are also used to counteract the after-effects of stimulant drugs such as opiates, ecstasy and amphetamines, and are known as “downers”. Benzodiazepines by themselves, although highly addictive, are relatively safe and most cases of overdose and death occur when the drug is taken in combination with other drugs or alcohol. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 3.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Recognizes Lorazepam. Reacts with ~11.07% Clonazepam, ~7.75% Nordiazepam, ~2.58% Oxazepam, <0.31% Temazepam, <0.31% Alprazolam, <0.31% g-Hydroxyalprazolam, <0.31% Nitrazepam, <0.31% 7-Aminonitrazepam, <0.31% Flunitrazepam.
- Supplied as an Ig fraction liquid in PBS, 0.09% sodium azide.
- Purified by ammonium sulfate precipitation.